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3 Wrinkle Products That Dermatologists Say Actually Work

The best wrinkle creams according to doctors

While your skin-care routine may currently be heavy with stuff to treat acne or get a covetable glow, it’s never a bad idea to incorporate products that prevent and treat signs of aging. “As we get older, our skin gets thinner, and produces less collagen and elastin — which means it doesn’t repair itself as well, and isn’t as plump or moist, which in turn causes our expression lines and wrinkles to stick around,” explains dermatologist Noelani Gonzalez, a specialist at Mount Sinai Health System. Wrinkle creams can be a great, all-around solution to the skin’s natural aging process because the best will both “provide support to your aging skin, and deliver ingredients to the skin that help it better repair and renew itself.”

To find the best wrinkle creams for preventing and treating fine lines, we spoke to Gonzalez and six other dermatologists. Read on for their picks, which include wrinkle creams with SPF, overnight wrinkle creams, ones specifically for under eyes, and more.

Best overall wrinkle cream












RoC Retinol Correxion Deep Wrinkle Anti-Aging Night Cream

Every dermatologist we spoke to agreed that the vitamin A derivative retinol is the most potent ingredient when it comes to getting rid of wrinkles (other important ingredients to look for are SPF, antioxidants, acids, and peptides). “When I think about the best anti-wrinkle creams, I immediately think about which over-the-counter creams contain retinols — which, in my opinion, are the No. 1 most important ingredient when looking for an anti-aging cream,” says Morgan Rabach, a dermatologist at LM Medical NYC. Dermatologist Marnie Nussbaum concurs that retinols are the “gold standard” and “one of the hardest working products — the MVP — in your beauty arsenal” for treating aging skin. That’s because retinols can help increase cellular turnover and encourage the formation of new skin, as well as the production of collagen and elastin, all of which help to reduce fine lines and wrinkles, according to Nussbaum. They also help fade discoloration, improve the appearance of pores, and repair UV damage.

Dermatologist Carlos A. Charles, the founder of New York City–based Derma di Colore, told us he typically suggests that patients use retinols’ prescription-strength cousin, retinoids, to treat wrinkles, but says that “in the over-the-counter world, RoC Retinol Correxion Deep Wrinkle Night Cream can be used for those who prefer a milder retinol formulation.” Rabach agrees, adding that the RoC is gentle enough to use on more sensitive, wrinkly skin around the eyes, too. When using a retinol, correct application is key to avoid irritating skin (which may still occur if you’re just starting out). According to Gonzales, start slow and apply pea-size, just two to three times a week, and work up from there. Nussbaum adds that it’s best to only use this (or any anti-aging cream with retinol) at night, since your skin has a better chance to repair itself while you sleep — and because retinol makes skin more sun-sensitive (so she additionally advises to wear a broad-spectrum sunscreen daily if you’re using retinol creams nightly).

#2 best wrinkle cream












Olay Pro-X Deep Wrinkle

“Slathering a moisturizer on every night will also help” plump wrinkles and fine lines, according to Rabach, who suggests Olay Regenerist for its thicker texture — which she notes is particularly good for wrinkly skin that’s also super dry. It is infused with hyaluronic acid, peptides, and niacinamide, all of which work together to plump and smooth fine lines. And if wrinkles are really stressing you out, Rabach adds that some small lifestyle changes can make a big difference. “Simple things like cutting down on smoking, hydrating when you’re out drinking, using a moisturizer every morning with sunscreen, and remembering to take off makeup will help reduce wrinkles over time.”

#3 best wrinkle cream












If you’re looking to treat particularly deep lines, say, around your mouth or in between your brow, they may likely require extra attention, according to dermatologist Samer Jaber, founder of Washington Square Dermatology. He told us that Olay Pro-X Deep Wrinkle is “an effective” option, but it’s admittedly more expensive than others on this list. However, Jaber pointed us to a 2010 study published in the British Journal of Dermatology that showed this cream effectively minimized facial wrinkles in just eight weeks, making it seem worth the price. He notes that this cream, which contains retinol, is also “fragrance-free, and has the anti-inflammatory vitamin niacinamide, which improves tolerability for those with sensitive skin.”